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In this work, Dr. Sims Wallace claims that "the cause of the prevalence of dental caries is that the natural food-stuffs are to a large extent ridded of their accompanying fibrous parts and prepared and consumed in a manner which renders them liable to lodge and undergo acid fermentation in the mouth."
Crowding of the teeth is a fruitful predisposing cause of caries acknowledged by Dr. Wallace, yet he attributes the crowding "to want of development of the tongue from lack of fibrous material in the food-stuffs. Removal of this fibrous material from the food-stuffs robs the tongue of a certain amount of activity, and so interferes with its development."
The trend of pathology is against the local influence on which so much stress is laid by Dr. Wallace and in favor of developmental elements. Caries is an expression of one senile tendency as opposed to another; of osteomalacia as
Cause and Prevention of Dental Caries.. JAMA. 1906;XLVII(5):377-378. doi:10.1001/jama.1906.02520050061020