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The case herewith reported possesses a double interest. It demonstrates the hitherto, I think, unreported injurious effect of the coal-tar derivatives on the sexual sphere and the danger of permitting the indiscriminate sale to the laity of dangerous drugs and nostrums.
—Mr. S. J., teacher, married, father of three children, consulted me Feb. 2, 1906, for loss of sexual power. For over a year he had been noticing a gradual diminution of the libidio sexualis, together with ejaculatio prœcox. He has been generally running down, losing flesh, etc.
—His complexion was sallow, dingy, cachectic. He tires very quickly, and gets out of breath on walking up stairs, or on running after a car. His tongue was heavily coated and breath was offensive. He had no appetite, bowels were constipated. He had had gonorrhea twelve years ago, but is apparently perfectly cured, there being no shreds in the urine
ROBINSON WJ. IMPOTENCE CAUSED BY THE EXCESSIVE CONSUMPTION OF BROMO-SELTZER.. JAMA. 1906;XLVII(7):508. doi:10.1001/jama.1906.25210070041003