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—Tuberculosis is clearly the disease whose chief anatomic lesions are tubercles, i. e., little tubers ("small potatoes" indeed) whose dire results are very great. They are minute, ovoid, obovoid or globular bodies, the products of biologic tissue invaded and preyed upon by a parasitic fungus whose infant state is generally deemed to be a bacillus and the mature form to be the mycoderma aceti, which generates acetic acid or vinegar. In other words, the action of the acetic acid of the vinegar plant itself and of the vitality of the invaded tissues result in hard little tubers (tubercles) as is well known. Like, but large tubers, are seen in plant biology; for example, the tumors on pear trees invaded by a fungous parasite, whose bacteria, mycelia and fruit (sporanges) penetrate the profoundest depths of the dense woody tissue, cambium and bark, as some twenty years ago I demonstrated by
CUTTER E. PREVENTION OF TUBERCULOSIS BY FEEDING.. JAMA. 1896;XXVI(10):461–463. doi:10.1001/jama.1896.02430620013002c