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March 14, 1896


Author Affiliations

CHICAGO. Late Assistant to Professor Erb, of Heidelberg; Professor of Nervous Diseases, Post-Graduate Medical School; Attending Neurologist, St. Elizabeth and Michael Reese Hospitals, Michael Reese Hospital Dispensary and U. H. C. West Side Dispensary: Consulting Neurologist, Home for Aged Jews and Home for Jewish Orphans.

JAMA. 1896;XXVI(11):516-518. doi:10.1001/jama.1896.02430630018002f

For some years we have known that syphilitic disease of the spinal cord may simulate the symptoms of locomotor ataxy. More recently we have learned that tabes dorsalis may occur simultaneously with true syphilitic lesions of the spinal cord or its membranes. In 1890 when examining the central nervous system of a patient who died while suffering from locomotor ataxy for changes in the cortex of the brain, such as had been described by Jéndrassik but a short time previously, I was surprised to find changes in the membranes of the brain and spinal cord, such as had not before been seen. The history of that remarkable case and the result of the microscopic examination were as follows:

The patient, a well-known actor, 36 years of age, had had an ulcus glandis penis when 20 years of age. He had a course of inunctions and never suffered from secondary symptoms.

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