[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.163.94.5. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
September 8, 1906

THE PATHOLOGY OF BILE.

Author Affiliations

NEW YORK CITY.

From the Department of Physiologic Chemistry, Columbia University.

JAMA. 1906;XLVII(10):765-767. doi:10.1001/jama.1906.25210100037002i
Abstract

That the bile is altered as a result of disease was noticed by Tacconi1 as far back as 1740. He remarked that in fever the bile changes in color and taste. Tacconi's observations were very few and superficial. Much more accurate were the studies of Uffelmann2 on the subject, carried out in 1874. He had the good fortune to make observations on the flow of bile from a patient with a biliary fistula who had an attack of pneumonia and noticed that the secretion of bile ceased with the onset of the disease. The same patient was later taken sick with dysentery. Again there was a disturbance of the activity of the liver. The secretion of bile almost stopped, he reported, with the manifestation of the disease.

Similar observations on the human subject were made more recently by Noel Paton and J. M. Balfour.3 About ten weeks

First Page Preview View Large
First page PDF preview
First page PDF preview
×