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Article
September 15, 1906

TREATMENT OF PROGRESSIVE ATROPHY OF THE OPTIC NERVE DUE TO ACQUIRED SYPHILIS.BY SUBCONJUNCTIVAL AND INTRAVAGINAL INJECTIONS OF SUBLIMATE OF MERCURY.

JAMA. 1906;XLVII(11):823-825. doi:10.1001/jama.1906.25210110007002a
Abstract

The treatment of syphilitic atrophy of the optic nerve is a subject which taxes all our patience and ingenuity. So universally unfavorable is the prognosis that the ophthalmic surgeon is ready to grasp almost any means which promises a solution of the problem. All surgical interference with the optic nerve itself, such as incision of the nerve sheath in several places, or elongation of the nerve by stretching, has yielded such imperfect and inconstant results that it can not any longer be recommended and has been abandoned. The same may be said of sympathectomy, which has so recently been vaunted as a remedy for atrophy. The constant current, and even static electricity, have been faithfully tried and have usually proved unavailing. Much has been claimed for the treatment by vibratory massage, but I have never personally known of a case of atrophy which has been permanently, or even temporarily, benefited

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