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June 4, 1904


JAMA. 1904;XLII(23):1498. doi:10.1001/jama.1904.02490680038011

An interesting subject considered at the recent meeting of the Association of American Physicians was that presented by Stengel1 on "Clinical Studies in Arteriosclerosis." According to Stengel's observations the first sign of beginning arteriosclerosis, which occurs at a considerable period before any thickening of the artery can be observed, is a prolongation of the first sound of the heart. With care this can be observed before the accentuation of the second sound. As it is at this period of the affection that prophylactic measures may be of real help, this observation would seem to be of the first importance for the treatment of a disease which so far has been considered rather out of the range of successful therapeutics. Another of the very interesting observations made is that in spite of the general impression to that effect, blood pressure in arteriosclerosis is not necessarily always high. The observations demonstrating

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