The treatment of hemophilia with the usual agents recommended for this disease, has been so ineffective that much difficulty has been experienced in arresting the hemorrhage from the slightest wounds, and many patients have died from the excessive loss of blood after the most trivial injuries.
The only advance in the therapy of this disease, has been made by Dr. E. A. Wright,1 who taking as a basis for his investigations the physiologic fact that a certain per cent. of calcium salts is necessary for the coagulation of the blood, made a series of experiments with calcium chlorid, and demonstrated its efficacy in increasing the coagulability of the blood.
In a later article the author reports the results of his examination of the blood of a case of hemophilia, and the coagulability of the blood before and after the administration of chlorid of calcium. He found that the blood
PERRY JC. THE TREATMENT OF HEMOPHILIA WITH CHLORID OF CALCIUM, WITH REPORT OF A CASE.. JAMA. 1897;XXVIII(11):492-493. doi:10.1001/jama.1897.02440110014002b