The infant deprived of the breast must, in relation to his feeding, be regarded as a pathologic problem. That this statement is axiomatic is shown by the fact that more earnest work has been bestowed on infant feeding during the past twenty years than on all other pediatric subjects combined. That the problem is still unsolved the high relative mortality and later morbidity of artificially fed infants bear constant witness.
The six essentials of Cheadle, enunciated by that observer some time in the '80s, bear witness that the essential requirements of an artificial food for babies were broadly understood 20 years ago. Quoting from memory, they are briefly as follows: 1. Sterility. 2. Antiscorbutic property. 3. Quantity. 4. Some animal constituents. 5. Form suitable. 6. Constituency. Much has been learned since Cheadle by amassing clinical results and observations. Meanwhile the deductions from a priori reasoning have proven unsatisfactory for the
COTTON AC. SODIUM CITRATE IN INFANT FEEDING.. JAMA. 1906;XLVII(14):1080–1083. doi:10.1001/jama.1906.25210140016001d