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Article
October 13, 1906

DANGER FROM THE CARELESS USE OF THE ALKALOID OF THE SUPRARENAL GLAND.

Author Affiliations

Aurist and Laryngologist to the German Hospital. PHILADELPHIA.

JAMA. 1906;XLVII(15):1188-1189. doi:10.1001/jama.1906.25210150044002

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Abstract

I feel that it is time to speak a word of caution and warning in regard to the indiscriminate and careless use of a preparation that is being widely advertised and prescribed as harmless, viz., the alkaloid of the suprarenal gland. In its proper field and under careful observation, this preparation is very valuable and of great assistance to the operator. But I feel that the present reckless use will result in harm and cast opprobrium on a really valuable remedy. Several cases that have come under my care have brought this sharply to my notice.

DANGER TO THE MUCOUS MEMBRANE.  Application of this remedy to the mucous membrane causes an intense shrinking in the caliber of the blood vessels, and when this effect wears away there is a dilatation to and beyond normal. The later effect of the preparation is to raise the blood pressure very decidedly, and when

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