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Article
July 4, 1896

AN INTRODUCTION TO THE DISCUSSION UPON "BLOOD-SERUM THERAPEUTICS."

Author Affiliations

PROFESSOR OF BACTERIOLOGY IN HARVARD UNIVERSITY.

JAMA. 1896;XXVII(1):14-17. doi:10.1001/jama.1896.02430790014001d
Abstract

Probably the most radical change in the ideas of the causation of disease that has ever occurred has taken place during the last thirty years, its final outcome being the subject of the discussion before this meeting to-day. The steps leading up to the position at present occupied have been taken only after many wanderings and painful experiences, but as a result we seem to have reached a rational standpoint from which further progress may be made. The basis of blood-serum therapeutics is the idea of immunity, and the procedure is the result of the investigations made to determine how immunity occurs. It had been known for a long time that after attacks of certain diseases, there was a period during which a second attack of this same disease did not occur. This was, and is, known as acquired immunity to the disease in question. Certain races of animals are

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