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During the past year a series of seventy-four carefully conducted experiments on the direct transfusion of blood in the treatment of hemorrhage in animals was made by Dr. Dolley and myself, and from these experiments the following conclusions were drawn:
Arteries and veins of varying sizes may be readily anastomosed by Carrel's method so as to be impervious to blood and free from clotting; the transference of blood from one animal to another is most definitely accomplished by anastomosing the proximal end of an artery of the donor into the proximal end of the vein of the donee; convenience need be the only consideration in the selection of the vessels to be anastomosed; the blood of one animal may be rapidly transfused to another; the blood of one dog is isontonic with that of another dog; if a dog be bled to the last drop of blood that will flow,
CRILE G. DIRECT TRANSFUSION OF BLOOD IN THE TREATMENT OF HEMORRHAGE.PRELIMINARY CLINICAL NOTE.. JAMA. 1906;XLVII(18):1482–1484. doi:10.1001/jama.1906.25210180058002