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Usually sarcomas arising in the uveal tract are slow in perforating the sclera and experience has taught us that, in their clinical course, they usually give rise to symptoms—interference with vision or glaucoma and the pain which goes with it—which attract attention to the condition before perforation of the sclera and extension to the orbital tissues take place. Accordingly the ophthalmic surgeon, as a rule, when he sees no gross perforation of the sclera, contents himself in dealing with uveal sarcomas by enucleating the affected eyeball. And this is good practice; for enucleation of the globe usually suffices, and the more radical procedure of exenterating the orbital contents, which theoretically, of course, would be more proper, is a far more serious operation and leaves the patient more deformed.
Sometimes, however, these growths go through the sclera comparatively early and sometimes macroscopically such extensions can not be made out. An experience
PUSEY B. A POINT IN THE MANAGEMENT OF UVEAL SARCOMAS.. JAMA. 1906;XLVII(26):2159-2160. doi:10.1001/jama.1906.25210260029002e