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New York, Dec. 22, 1906.
To the Editor:
—On looking over a few of the latest prescription files at several drug stores, I was surprised to find that many physicians still prescribe tincture of aconite in the old doses.Most druggists by this time have the new official tincture of 10 per cent, strength; and of this they dispense the quantity as prescribed. The result must, of necessity, be disappointing to both physician and patient, since a tincture of 10 per cent, can not have the same therapeutic effect, in the same doses, as a tincture of 35 per cent.Some physicians not only did not know that the strength of this tincture had been reduced, but were entirely innocent of the existence of the new Pharmacopeia.One physician who happened to prescribe tincture of aconite in five minim doses, in my presence, thought he was heroic in his doses.
Buckle L. Prescribing Aconite by the Old Pharmacopeia.. JAMA. 1906;XLVII(26):2170. doi:10.1001/jama.1906.02520260040010