Gonorrheal arthritis is a specific infection of one or more joints, occurring as a sequela or complication of gonorrhea, usually in its subacute or chronic stages, only a very limited number of cases having been reported during the acute stage of gonorrhea. The oft repeated expression that this disease is not equal to a "bad cold" must be corrected by the profession. The falsity of this description is quickly appreciated by its unfortunate victim, should arthritis develop, as few joint troubles are so painful. The infection is transmitted usually by the blood, and therefore is a general infection in which the joint pathology is but a local manifestation, and while the local symptoms are the principal ones to attract the attention of both patient and physician, my observation is that the general system suffers far more seriously than is usually appreciated.
The infective agent is primarily the gonococci, or
WITHERSPOON JA. GONORRHEAL ARTHRITIS.. JAMA. 1907;XLVIII(5):377-378. doi:10.1001/jama.1907.25220310001001