Perhaps many of you will think of the celebrated chapter on "Snakes in Iceland" in connection with the title assigned to me. Most authors on the subject say little or nothing in line with the view suggested, some dismiss it by saying that arteriosclerosis is a common cause but rarely a result of nephritis, while others say that nephritis and arteriosclerosis are often combined and due to the same cause. A few admit that nephritis may cause arteriosclerosis by the prevention of elimination and the throwing into the circulation of substances that either injure the walls of the arteries directly or increase vascular tension, so causing hypertrophy of the heart, high pressure and later disease of the arteries.
It is doubtless true that in many cases the arterial disease causes the renal disease. It is of great clinical importance that the kidney lesion may
DOCK G. ARTERIOSCLEROSIS OF NEPHRITIC ORIGIN.. JAMA. 1904;XLIII(11):730. doi:10.1001/jama.1904.92500110001f