September 10, 1904


JAMA. 1904;XLIII(11):741. doi:10.1001/jama.1904.02500110035008

The subject of arteriosclerosis is one of perennial interest, and one concerning which, in spite of the immense amount of study which has been devoted to it, much yet remains to be cleared up. It has recently been discussed in Germany before the Congress for Internal Medicine,1 and in this country before the Pathological Society of Philadelphia2 and the American Medical Association.

The paper of Marchand before the German congress, which discusses the subject in its wider pathologic aspects, considers under the term arteriosclerosis all those changes in the arteries which lead to a diffuse or nodular thickening of the wall, especially of the intima, in the development of which degenerative, sclerotic and calcareous changes occur. This conception necessarily excludes pure hypertrophy of the media, and syphilitic processes occurring in the medium sized and small arteries. The essential factor which is at the bottom of all cases of

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