Of all diseases of the eye probably syphilis is responsible for a greater number of ocular affections than any one disease known, so I can not, in a paper of this character, go into an exhaustive study of diagnosis, prognosis and treatment, but will confine my remarks to giving the essentials of diagnosis, and take up each subject as seen from the anterior aspect of the eye.
Secondary syphilitic ulcers may occur in the eyelids from the breaking down of a gumma originating in the skin or in the subcutaneous tissue and cartilage. The most frequent location of the lesion is in the skin, near the lid margin or below the inner canthus, though it may occur on the conjunctival surface of the lid. It manifests itself usually at a late stage of the disease and should be classified as a tertiary lesion. The fact that this lesion may
BRUNSON R. SOME SYPHILITIC DISEASES OF THE EYE.. JAMA. 1907;XLVIII(14):1160-1163. doi:10.1001/jama.1907.25220400012001c