The invasion of carcinoma cervicis uteri into the surrounding tissue manifests itself clinically in the large percentage of the cases in which the disease is not recognized until after it has extended beyond operative treatment, and also in the still larger percentage of the cases in which the disease returns after operation, showing that at the time of the operation the surrounding tissues had already become involved, and on this account hysterectomy seldom cures the disease.
It is little wonder that the laity and even some physicians consider cancer of the cervix of the uterus an incurable disease, for over three-fifths of the patients admitted to this hospital with carcinoma cervicis uteri come too late for anything but palliative treatment, and probably over three-quarters of the patients operated on will die from cancer within five years of the operation. Our only hope of bettering this condition is in an earlier
SAMPSON JA. THE INVASION OF CARCINOMA CERVICIS UTERI INTO THE SURROUNDING TISSUESAND ITS BEARING ON THE MORE RADICAL OPERATIONS FOR THAT DISEASE.. JAMA. 1904;XLIII(18):1271-1275. doi:10.1001/jama.1904.92500180001