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November 12, 1904


JAMA. 1904;XLIII(20):1454-1456. doi:10.1001/jama.1904.92500200001g

Erythema nodosum is a disease of childhood which is of interest to the dermatologist as well as to the practitioner who treats sick children. The disease was first termed erythema nodosum by the French physician, Eobert Willan. In his text-book on "Diseases of the Skin and Their Treatment," which appeared in the year 1799, the foregoing name is applied to this disease. The older authors, however, paid little heed to the constitutional symptoms which were present; they were more particularly concerned about the lesion of the skin. They believed that this was a variety of the erythema group. Trousseau pointed out that erythema nodosum differed from the general erythema group in its form, location and in its clinical course. Modern dermatologists differ among themselves as to the relation of erythema multiforme and erythema nodosum; for example, Lesser believes that the two are to be distinctly separated. In the same manner

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