Unconsciously the skin receives a good deal of attention from the general practitioner in connection with many disordered or diseased conditions of the system, and yet when the skin itself becomes diseased many physicians seem to lose sight of its relation to the general system, and regard and treat it only locally; and this happens often, much to the detriment of the patient, and too frequently with unsatisfactory results in regard to the cutaneous affection.1
One need only mention the exanthemata to suggest at once that phenomena on the skin may be only one evidence of disease, while the dry skin of fever and the sweating at a crisis and in tuberculosis show the important part which the skin has in the economy, and many such illustrations will occur to all.
Although we may not recognize it, nor be conscious of it, the skin eventually plays a most important
BULKLEY LD. DANGER SIGNALS FROM THE SKIN.. JAMA. 1907;XLVIII(21):1740–1743. doi:10.1001/jama.1907.25220470008001c