Tuberculin and antitoxic serum are, strictly speaking, the only real specifics related to tuberculosis. I shall, therefore, restrict my observations to these and endeavor to present some thoughts on their rational use, limitations and value in the light of our present knowledge of their effects. I must state at the outset that my personal experience with these methods is for the most part confined to laboratory and experimental observations. Whatever may be thought by some of the value of such observations, it must be remembered that man has not been found an exception among animals in the application of the general principles worked out by animal experimentation.
In order to formulate some ideas about the propriety of employing tuberculin as a treatment, one should first consent to an unprejudiced investigation of its utility and danger. Ignorant haste, both in its use and condemnation, characterizes the history of tuberculin treatment, for
BALDWIN ER. THE RATIONAL APPLICATION AND VALUE OF SPECIFIC TREATMENT FOR TUBERCULOSIS.. JAMA. 1904;XLIII(22):1600–1604. doi:10.1001/jama.1904.92500220001b