June 1, 1907


JAMA. 1907;XLVIII(22):1869-1870. doi:10.1001/jama.1907.02520480047011

It can not be said that a final decision has been reached with respect to the etiology of acute pancreatitis. Many causes have been assigned for this disorder, but there has been so little constancy in the activity of any of the factors held responsible that for the present it must be concluded that a considerable number of these are operative under different conditions. These causative factors may be divided into three groups, comprising: (1) Obstruction of the biliary or pancreatic ducts, with retrojection of secretion; (2) infection from the gastrointestinal tract or contiguous disease or through the general system; (3) traumatism. Fat necrosis and glycosuria are not uncommon complications. As the result of an analysis of 105 cases of acute pancreatitis recorded in the literature, Dr. Anfin Egdahl,1 who reports two additional cases, reaches the conclusion that gallstones are probably the most common single cause of acute pancreatitis—these

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