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Article
January 28, 1905

AUTOGENOUS REGENERATION OF NERVES.

JAMA. 1905;XLIV(4):296-297. doi:10.1001/jama.1905.02500310040003

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Abstract

The experiments of Bethe of Strassburg are attracting, and rightly, the attention of neurologists to an unusual degree. It would appear that Bethe has definitely established the fact that, on section of a peripheral nerve trunk, the distal portion can regenerate, in young animals at least, without any connection with the central stump. He has made a large series of experiments on the sciatic and other nerves. He excises long pieces and transplants the central stump so as to render any subsequent union with the distal trunk impossible. He has demonstrated that the myelin sheath and neurofibrils as well as the axon regenerate; he has shown that when regenerated the nerves are capable of conducting impulses; and more, that if the regenerated fiber be cut again the peripheral portion degenerates to the periphery, while its central portion, unconnected with either center or periphery, remains for a long time undegenerated. Conscientious

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