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It has been repeatedly held that the sound skin will absorb substances in watery solution, and again it has been denied. The teaching of our standard text-books for the past dozen years has been that of Parisot, who said that the skin was unable to absorb any substances from watery solutions, and that this was due to the fat nominally present in the epidermis and pores of the skin. According to Röhrig all substances which act upon and corrode the skin, are capable of absorption. This fact was later confirmed by Ritter and Pfeiffer, who found that salicylic acid was rapidly absorbed when brought in contact with the skin, and other substances brought in contact with a part previously treated with salicylic acid, rapidly entered the circulation. The experiments of these writers would seem to be conclusive as to the impossibility of substances passing through the sound skin. In only
ABSORPTION BY THE SKIN.. JAMA. 1890;XV(15):543. doi:10.1001/jama.1890.02410410023004