In studying the pathology of drug addiction, it seems to me we have a threefold problem to solve. First, there is the hereditary abnormal aspect—the psycho-cellular pathology; second, the acquired abnormal conditions of the individual, which lead to the use of drug stimulants—the pseudo-pathology; and, third, the effect on the system of the particular drug used—the true pathology of the addiction.
I am perfectly well aware that good authorities deny the influence of heredity among drug habitués, but I do not believe that this ground can well be maintained. First of all, it is a matter of record in the study of the histories of a large percentage of habitués of all kinds, that we find taints of varying degree among the ancestors of these individuals. It is a matter of very common occurrence to learn that either one or both parents
STERNE AE. HAVE DRUG ADDICTIONS A PATHOLOGIC BASIS?. JAMA. 1905;XLIV(8):609-612. doi:10.1001/jama.1905.92500350019001e