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April 4, 1891

SOME OF THE LESIONS INDUCED BY TYPHOID FEVER.Read before the Cambridge Society for Medical Improvement, February 23, 1891.

Author Affiliations


JAMA. 1891;XVI(14):473-476. doi:10.1001/jama.1891.02410660005001a

Perhaps no disease whose records have been embodied in medical literature is attended or followed by a greater variety of lesions than is that of typhoid fever. The functions of the great nerve centres, including the brain and spinal cord, as also those of the nervous system generally, are liable to be seriously influenced, weakened or interrupted, for periods of uncertain duration, by the occurrence of an attack of typhoid fever.

Among the sequels or complications that have been observed is dementia, insanity, loss of sight, aphasia, paraplegia and other forms of paralysis. Sometimes only one limb, as a leg or an arm; rarely, only an arm and a leg at the same time. At other times disturbances are limited to the functions of speech. Cases now and then occur, in which we have paralysis without appreciable anæsthesia. The more common forms are those in which both the motor and

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