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The fact that the nasal condition was the only reason why this patient sought relief and that this seems to be so entirely dependent upon the general disorder leads me to report the history, which is as follows:
Mrs. I., age 38, was first seen Sept. 9, 1896. She complained of nasal stoppage with attacks of sneezing and watery discharge following an attack of grippe in May and persisting since then. For the past three weeks it had been worse. Examination of the nostrils at this time showed large boggy turbinates on both sides, rather worse on right, with a waxy paleness of the entire mucous membrane of the nostrils. Several constitutional remedies, as well as local applications, were tried in succession without the slightest effect on the condition. Oct. 26, 1896, frost having eliminated a possible hay fever and the hoped-for improvement not having occurred, I examined the nostrils
CLEVELAND AH. A CASE OF MYXEDEMA WITH PROMINENT NASAL SYMPTOMS.. JAMA. 1898;XXX(10):542-543. doi:10.1001/jama.1898.72440620030001k