This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.
It is stated in a German pharmaceutical journal that piperazidine dissolves uric acid more readily than any other substance of a basic nature. Urate of lithia requires 368 times its own weight of water to dissolve it, but urate of piperazidine dissolves in fifty times its weight of water. It may therefore be expected that this drug will become a fashionable, let us hope, too, an efficient remedy in gout and allied diseases.
PIPERAZIDINE AS A SOLVENT FOR URIC ACID.. JAMA. 1891;XVI(21):754. doi:10.1001/jama.1891.02410730034012