June 13, 1891


JAMA. 1891;XVI(24):855-856. doi:10.1001/jama.1891.02410760027002

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Mode of Entry of the Tubercular Poison into THE Body.  —A very good' summary of the various paths of infection adopted by the tubercle bacillus is given by C. Bollinger in the Münchener Med. Wochenschrift, 1890, No. 43. He considers that the frequency of infection through the skin has been under-estimated. Several cases have been recorded of direct inoculation by wounds received from broken spittoons, etc., by bites, after circumcision, by morphia syringes, and earrings. Eczema and impetigo increase the susceptibility of the skin. No case has as yet been attributed to vaccination, and it would appear that the tubercle bacilli are unable to live in the vaccine lymph. They also appear unable to pierce the pores of the skin as do some of the pyogenic organisms. The susceptibility of the mucous membrane is increased by inflammatory processes, such as otitis, rhinitis, conjunctivitis, pharyngitis, etc; from thence the poison travels

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