During the past eleven years I have conducted and experimental laboratory, in which some of the problems suggested in surgical practice have been investigated. On some we failed to throw any light; in some our results were inconclusive; and in others therir solution seemed to have been found, or at least useful data obtained. These were published in four monographs, to wit: "Surgical Shock," 1897; "Research into the Surgery of the Respiratory System," 1899; "Problems Relating to Surgical Operations," 1901; "Blood Pressure in Surgery," 1903.On the clinical side during a corresponding period, we accumulated notes on 5,800 major operations in general surgical service, including every variety excepting certain operations on the eye and ear.The discussion of the various operations is only from the restricted viewpoint of the title of this paper. In the experimental as well as the clinical Work my associate, Dr. W. E. Lower, was actively engaged during this time and shares fully with me the responsibility for the results.
CRILE GW. THE PREVENTION OF SHOCK AND HEMORRHAGE IN SURGICAL PRACTICE.. JAMA. 1905;XLIV(24):1925-1927. doi:10.1001/jama.1905.92500510033001i