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April 2, 1898


JAMA. 1898;XXX(14):800-801. doi:10.1001/jama.1898.02440660048007

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Not many years ago, physicians were as much accustomed to declare a patient "slightly anemic" as to ascribe the symptoms of another unfortunate to "a touch of the malaria." As we know that the latter disease exhibits different varieties and a vast number of anomalous symptoms, and that we are justified in making a diagnosis of ague only after finding the plasmodium in the blood, so we have learned that in anemia there are many forms whose symptoms are so similar that they can frequently be recognized only by most careful hematologic examination.

A thorough and systematic examination of the blood involves more time and skill than that of any other tissue of the body. Before one has accomplished such a feat he must have examined the fresh blood, dried and stained covers, counted the red and white corpuscles, estimated the amount of hemoglobin, the relative volumes of corpuscles and

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