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Yellow fever is thought to be a microbic disease, and to depend upon the chemical products of these microörganisms for its deleterious action upon man. It is a fact that these microbes and their products cannot be destroyed while in man by any known drug, nor can their ptomaines be neutralized while in the organism by any chemical not primarily destructive to man. In the absence of any known specific for yellow fever, to my own knowledge and experience it is evident that the best curative results are obtained by a depurative eliminative treatment, acting through the skin, bowels, and kidneys.
Our epidemic at Jacksonville in 1888 was an exact repetition of the New Orleans epidemic of 1867. In both there were sporadic cases in the early spring; the types were generally mild; the fever was most sweeping, including the negroes, who are generally exempt. One attack here in 1877,
CENTER GF. NOTES ON YELLOW FEVER.. JAMA. 1892;XVIII(6):156-160. doi:10.1001/jama.1892.02411100004001a