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November 3, 1900


JAMA. 1900;XXXV(18):1158-1159. doi:10.1001/jama.1900.02460440032003

Scarcely less important than the recognition of organic disease is an appreciation of the degree of functional derangement present. Some attempts in the determination of the latter have been attended with success, and the kidneys, by reason of the opportunities for comparison they offer, would seem to be especially suitable for this means of study. The information thus gained would be useful from both the prognostic and the therapeutic point of view. Two questions will at once arise: 1. What is the functional efficiency of the kidneys; and is it sufficient for the purposes of the organism? 2. What part does each kidney take in this function? The desired information may be gained by catheterizing the ureters, which will permit not only a study of the microscopic and chemic constitution of the urine, but also an estimate of the functional activity of each kidney. Caspar and Richter1 report the

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