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Article
December 21, 1901

A STUDY OF A FETAL STOMACH, WITH SPECIAL REFERENCE TO THE ORIGIN OF ACID SECRETING CELLS.

JAMA. 1901;XXXVII(25):1674-1675. doi:10.1001/jama.1901.62470510030001i
Abstract

This specimen was examined with a view to determining the origin of the acid cells. It is proper to begin by considering the origin of the hydrochloric acid. We assume that the works of Wesener and others have demonstrated that the acid is derived not from the food, but from the cells of the stomach wall.

Assuming then that it is proven that the acid is secreted, we pass to the question as to whether the acid is in combination with the ferment. A review of the literature convinces us that there is a loose chemical combination between them. Where is this combination effected? Is it in the same cell, or are there different sets of cells—one secreting ferments, another acid. Again, we conclude that there are different cells.

If there is a division of function, which cells are secreting acid, and, as a subsidiary proposition, whence are these cells

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