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Article
January 25, 1902

AUTO-NEPHROTOXINS IN OPERATIONS UPON THE KIDNEYS.

JAMA. 1902;XXXVIII(4):254. doi:10.1001/jama.1902.02480040040007
Abstract

In view of the frequency with which the kidney and connected structures are subjected to surgical operations of various kinds it may not be without interest to recall certain results obtained from experimental operations in this field. Castaigne and Rathery1 find that in unilateral nephrectomy of rabbits the mortality is very small—in 12 cases only one death, and that was from post-operative peritonitis. On the other hand, unilateral ligature of the renal artery, of the ureter, or of the entire mass of the pedicle of the kidney is followed by a much greater mortality, namely, 34.8 per 100. In these cases death could not be ascribed to any other causes than such as were directly connected with or dependent upon the ligatures, and it would appear as if the kidney, compromised by the tying of its vessels or of its ureter, or both, constitutes a source of danger for the

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