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August 13, 1898

THE HISTOLOGIC CHANGES PRODUCED BY THE VENOM OF POISONOUS SNAKES AND LIZARDS.

JAMA. 1898;XXXI(7):358-359. doi:10.1001/jama.1898.02450070036005
Abstract

There is quite a remarkable resemblance, in many respects, between the toxic substances produced by microbes, by certain plants, as well as by certain animals. It has been well established that animals can be made immune, not only against microbic toxins, but also against venoms of different origin. Thus, Ehrlich has immunized animals against ricin and abrin, and Calmette against the poison of venomous snakes.

There are also certain chemic resemblances between the toxins of various origin, especially in their feeble resistance to heat. There has also been found a certain similarity between the lesions produced in the animals killed by these various poisons. The changes produced in the tissues by the poisons of serpents and lizards have, however, not received very much attention, if any. Nowak's1 recent experimental study of the histologic alterations produced by snake venom and by the poison of lizards is therefore especially interesting.

The

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