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Curiously enough, while the tendency in modern civilization is to eliminate the distinctions in the political and economic status of men and women, that of medicine has been to exaggerate the natural difference of the manifestation of disease between the sexes.
The object of this essay is not so much to show how many as how few are the differences. The influence of sex on the course of general disease is wholly a matter of soil and environment; that is, the disease is the same, with the same tendencies and possible terminations, but modified by the constitution of the person and not by sex. Granted that individual constitution does affect the course of disease, we must determine whether its characteristics differ according to sex, or whether they differ among individuals regardless of sex. To predict our conclusions it will be found that the course of general diseases is not affected
BISHOP LF. THE INFLUENCE OF SEX ON DISEASE.. JAMA. 1898;XXXI(12):643–644. doi:10.1001/jama.1898.92450120017002g