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October 15, 1898


JAMA. 1898;XXXI(16):892-899. doi:10.1001/jama.1898.92450160011002b

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The last decade has been very fruitful as regards the introduction of intestinal antiseptics and astringents. To comprehensively describe each and every one introduced during this period, would be beyond the scope of a paper the reading of which will not prove tiresome to the listeners. I will therefore confine myself to those which have made their first appearance during the past five or six years. The modern intestinal antiseptics and astringents belong chiefly to one of two classes of preparations: derivatives of tannic acid, or salts of bismuth. The former will be alluded to first, the articles being described in the order of their introduction into the materia medica.

Among internal astringents tannic acid has long occupied a prominent position; but it has a number of serious drawbacks, chief among which is that it acts undesirably on the mucosæ of the mouth and stomach, where the larger portion of

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