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Glandular physiology in its widespread ramifications has revolutionized many parts of physiology and pathology. It is only in its infancy and its maze of metabolic changes holds many facts to be discovered. The secretion of the ductless glands opens up new avenues of investigation, which will enrich the science of physiology and the practical application of these facts in therapeutics. We have a silent and hitherto unsuspected secretion going on which plays a most important and unknown part in our economy. Very potent remedies are the ductless glands, where but a few thousandths of a grain of a gland like the pituitary greatly elevates the arterial tension. I have made over one hundred experiments upon the lower animals with the various extracts obtained from Armour & Co. of Chicago. The experiments upon the reflexes were made upon frogs, those on pulse pressure, respiration and temperature upon rabbits. The results were
OTT I. GLANDULAR EXTRACT.. JAMA. 1898;XXXI(16):918. doi:10.1001/jama.1898.92450160037002n