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When it was found, not a great many years ago, that the presence of eosinophilic cells in the blood was not only not a characteristic symptom of leukemia, but that these cells were a constant constituent of normal blood, interest in them was to a large extent dissipated. Only of late, since the findings of Osler, Thayer and Cabot, of an enormous increase of these cells in the blood of patients afflicted with trichinosis, has anything like general interest been excited. But during this interval much work has been accomplished in blood histology and pathology, and not a few important points have been established as regards the eosinophiles. While the eosinophiles may be always found in the healthy circulating blood, yet their proportion to the various forms of white cells exhibits a considerable range, from one-fourth of 1 per cent. In infancy even this ratio may be exceeded, so that
EOSINOPHILIA.. JAMA. 1898;XXXI(17):991-992. doi:10.1001/jama.1898.02450170045006