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January 21, 1899


JAMA. 1899;XXXII(3):136. doi:10.1001/jama.1899.02450300038008

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Some months ago the Journal referred editorially to some experimental researches on toxins and antitoxins by two English investigators, Drs. Martin and Cherry, by which it seemed to be demonstrated that the counter-action of these substances is a chemic and not a vital one, it occurring as well in vitro as in corpore. Dr. Martin has recently published (Proc. Royal Soc., lxiv, 88) some further investigations, which supplement the above and throw additional light on some of the practical questions involved.

His experiments were made, like some of his earlier ones, with the venom of an Australian snake, Hoplocephalus Curtus and with a corresponding antitoxin prepared by Calmette. In his former researches he had found that there exists a decided difference in the molecular sizes of venoms or toxins and antitoxins, and had conjectured that while the former are albumoses, the latter may be globulins. That snake venoms are albumoses

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