On Feb. 2, 1899, I was called to see a two-year-old child who had been ill for four days, without medical attention, and found I had to deal with a grave case of scarlet fever. The temperature was 105 F.; there was a severe angina with the characteristic exudate in the pharynx, on the tonsils and soft palate, and the cervical glands were moderately enlarged. The subsequent course of the disease was severe. The pharyngeal exudate extended into the posterior nares and, finally, into the middle ear, with perforation of both tympani; accompanied by a profuse purulent discharge from the external auditory canals and from the nose. The rectal temperature was alone taken, and ranged from 104 to 105, and, Feb. 15, rose as high as 106.5.
The treatment consisted of frequently administered baths, each of fifteen minutes' duration, and gradually cooled from 100 to 90, or even 85
LANDIS EM. SCARLET FEVER.TREATED WITH ANTISTREPTOCOCCIC SERUM; RECOVERY.. JAMA. 1899;XXXII(14):760. doi:10.1001/jama.1899.92450410020002e