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Article
January 27, 1900

THE TREATMENT OF ANEURYSMS BY SUBCUTANEOUS GELATIN INJECTIONS.

Author Affiliations

Associate in Medicine, Johns Hopkins University; Resident Physician to Johns Hopkins Hospital. BALTIMORE. MD.

JAMA. 1900;XXXIV(4):204-209. doi:10.1001/jama.1900.24610040014001d
Abstract

The year 1898 added still another to the many methods that have been advanced to the treatment and cure of aneurysms. To Lancereaux of Paris is due the credit of having introduced this method to the medical profession. The treatment in question consists in the injection of sterilized solutions of gelatin into the subcutaneous tissues.

The method is based on the experimental work of Dastre and Floresco1, who studied the effect of gelatin solutions on the coagulability of the blood. These observers went only so far as to show that the coagulability of the blood was increased when the gelatin solution was brought into direct contact with it, whether this be the circulating blood of the animal or the blood of the animal after removal. They found that the injection of gelatin solutions into the blood-vessels of dogs and rabbits caused a rapid coagulation of the blood. They employed

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