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February 3, 1900


JAMA. 1900;XXXIV(5):302. doi:10.1001/jama.1900.02460050048013

Dieulafoy2 describes a rare but interesting form of pneumococcus infection, namely the gastric. Ulcerations of the stomach are occasionally seen in autopsies of cases of pneumonia, but Dieulafoy is the first to demonstrate that the pneumococcus is the actual cause of and present in such ulcerations of the human stomach. Bezançon and Griffon have shown that ulcerations may develop in the stomach of guinea-pigs experimentally infected with the pneumococcus. Of two patients with multiple serositis caused by the pneumococcus and presenting severe hematemesis during life, he found in one numerous small ulcers of the stomach reaching to the muscularis mucosæ, surrounded by an inflammatory zone; numerous pneumococci were present in the tissue of the floor and margins of the ulcers, and in the surrounding intertubular glandular tissue, even for some distance from the ulcers. In the second there were hemorrhagic extravasations in the mucosa, but pneumococci were not present.

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