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April 21, 1900


Author Affiliations

Professor of Obstetrics and Gynecology in Rush Medical College. CHICAGO.

JAMA. 1900;XXXIV(16):959-962. doi:10.1001/jama.1900.24610160001001

CHANGES IN THE KIDNEYS DURING PREGNANCY.  For many years there has been much discussion as to the alterations occurring in the kidneys during pregnancy, and, at the present time, there is considerable difference of opinion as to the nature of these changes, their frequency, causation and significance. The literature of the subject is abundant in speculative inquiries, while records of trustworthy facts derived from careful and systematic observation are scanty. Indeed, though theories have multiplied, it is doubtful whether we are very much wiser than we were fifty years ago, for the latest and most favored views, originating among French workers, are only an elaborated expression of the opinion published by Virchow in 1848.This authority then pointed out that, of all the organs in the female organism, the most frequent functional or structural alterations due to pregnancy were found in the kidneys. He regarded the cause mainly as connected

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