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To the Editor:—
I believe that you meant to use "hypothesize," "to adopt as a hypothesis." Hypothecate means, roughly, to pawn (Oxford Universal Dictionary). William Boyd made the same error in his Textbook of Pathology when I was a medical student (about 1933).
Harvey RK. To Have Been or Not to Have Been. JAMA. 1965;191(6):504. doi:10.1001/jama.1965.03080060078026