March 8, 1965

Plasma Renin Activity in Primary Aldosteronism-Reply

Author Affiliations

Ann Arbor, Mich

JAMA. 1965;191(10):868-869. doi:10.1001/jama.1965.03080100085038

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To the Editor:—  We are pleased with the opportunity to respond to the letter submitted by Drs. Brown, Davies, Lever, and Robertson, conconcerning two papers from my laboratory which appeared in the Oct 19, 1964, issue of The Journal.The first paper, by me and two of my colleagues, presents carefully collected data, together with our interpretation of them. Dr. Brown and his colleagues raise no serious objection to the major points of this paper or to the conclusions that we have drawn from our data. In fact, they suggest that they had come to the same conclusions before we had. While this is not correct, we are not concerned with the question of priority and are pleased that the two groups agree that a hypertensive hypokalemic patient, exhibiting both overproduction of aldosterone and a suppressed capacity to release renin into the blood, has primary aldosteronism.The second paper (which

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