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A team of investigators at the University of Florida College of Medicine is substituting a drug regimen for surgical intervention in certain cases of acute dissecting aneurysms of the aorta.
In six consecutive cases in which the new therapy has been used, all patients are surviving 9 to 15 months later, the Florida group told the annual meeting in New Orleans of The American Association for Thoracic Surgery. Surgery has been performed on only one of the six patients, and that was on an elective basis nine months after diagnosis.
In contrast, death occurred within five days after surgical repair in each of six earlier consecutive cases in which the drug therapy was not used.
Describing the series of surviving patients, Myron W. Wheat, Jr., MD, chief of thoracic and cardiovascular surgery at Florida, told The Journal: "By rights, most or all of these patients should be dead."
New Drug Therapy Replaces Surgery In Some Dissecting Aortic Aneurysms. JAMA. 1965;192(3):33–35. doi:10.1001/jama.1965.03080160101055