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May 3, 1965

Ureteral Vascular Rejection in Human Renal Transplants

Author Affiliations

From the Department of Pathology, Northwestern University Medical School, and Passavant Memorial Hospital, Chicago.

JAMA. 1965;192(5):417-419. doi:10.1001/jama.1965.03080180075028

THE URETER is an integral part of the human renal transplant. Previous studies have noted vascular abnormalities in the kidneys of patients with rejected renal transplants.1-3 However, these reports have not commented upon the presence or absence of similar changes in the ureter. Microscopic studies of the ureter in two patients who have died with homotransplanted kidneys showed rejection type vascular changes not unlike those described in the kidneys.1-3

Report of Cases 

Case 1.—  A 51-year-old man was admitted to the hospital because of arterial and arteriolar nephrosclerosis, intercapillary glomerulosclerosis, hypertension, and terminal uremia. These conditions were diagnosed 16 months prior to this hospital admission and there was slight improvement with periodic hemodialysis and intermittent peritoneal dialysis. The patient was admitted to Passavant Memorial Hospital in October 1964 for renewal of his hemodialysis regimen. At this time his blood pressure was 218/104 mm Hg. Blood sugar levels ranged

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